NRHS contributor

Dr Fredrick Mak'Otieno

Kisumu, Kenya

Dr Fredrick Mak'Otieno contributes to research, programmes and public health communication at the Nyanza Reproductive Health Society.

12published articles

From the author

Articles and updates

Research, stories and organisational updates published by Dr Fredrick Mak'Otieno.

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NRHS Annual Report 2024: A Year of Impact, Innovation, and Community

The Nyanza Reproductive Health Society (NRHS) is proud to share our 2024 Annual Report, capturing a year of resilience, innovation, and measurable impact in advancing reproductive health and HIV prevention across Kenya. Founded in 2002, NRHS has grown into a leader in evidence-based programming, cutting-edge research, and policy advocacy—anchored in our vision of a world where individuals and communities enjoy the highest possible quality of life. Reaching Thousands With Life-Saving Services

NRHSResearch • Evidence • Impact

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Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial

Randomized Controlled Trial Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Robert C Bailey, Stephen Moses, Corette B Parker, Kawango Agot, Ian Maclean, John N Krieger, Carolyn F M Williams, Richard T Campbell, Jeckoniah O Ndinya-Achola Lancet. 2007 Feb 24;369(9562):643-56. PMID: 17321310 DOI: 10.1016/S0140-6736(07)60312-2 Background: Male circumcision could provide substantial protection against acquisition of HIV-1 infection. Our aim was to

NRHSResearch • Evidence • Impact

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HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections

HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections. Betty A Donoval, Alan L Landay, Stephen Moses, Kawango Agot, J O Ndinya-Achola, Edith A Nyagaya, Ian MacLean, Robert C Bailey. Am J Clin Pathol. 2006 Mar;125(3):386-91. PMID: 16613341. https://pubmed.ncbi.nlm.nih.gov/16613341/ Numerous epidemiologic studies have found significant associations between lack of circumcision and HIV-1 acquisition in men. To our knowledge, this is the first stud

NRHSResearch • Evidence • Impact

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Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya

Adult male circumcision: results of a standardized procedure in Kisumu District, Kenya. John N Krieger 1, Robert C Bailey, John Opeya, Benard Ayieko, Felix Opiyo, Kawango Agot, Corette Parker, Jeckoniah O Ndinya-Achola, George A O Magoha, Stephen Moses. BJU Int. 2005 Nov;96(7):1109-13. PMID: 16225538 DOI: 10.1111/j.1464-410X.2005.05810.x Objective: To develop a standard procedure for male circumcision in a resource-poor medical setting and prospectively evaluate the outcome in a randomized, con

NRHSResearch • Evidence • Impact

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Acceptability of male circumcision and predictors of circumcision preference among men and women in Nyanza Province, Kenya

Acceptability of male circumcision and predictors of circumcision preference among men and women in Nyanza Province, Kenya C L Mattson, R C Bailey, R Muga, R Poulussen, T Onyango. AIDS Care. 2005 Feb;17(2):182-94. PMID: 15763713 DOI: 10.1080/09540120512331325671 Numerous epidemiologic studies report significant associations between lack of male circumcision and HIV-1 infection, leading some to suggest that male circumcision be added to the limited armamentarium of HIV prevention strategies in a

NRHSResearch • Evidence • Impact

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Feasibility of medical male circumcision in Nyanza Province, Kenya

Feasibility of medical male circumcision in Nyanza Province, Kenya. CL Mattson, R Muga, R Poulussen, T Onyango, RC Bailey East African Medical Journal Vol. 81 No. 5 May 2004: 230-235 DOI: https://www.ajol.info/index.php/eamj/article/view/9165 Background: Over forty observational studies have reported a protective effect of male circumcision against HIV-I acquisition, leading some to suggest that male circumcision be added to the limited armamentarium of HIV prevention strategies. Objectives: To

NRHSResearch • Evidence • Impact

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Susceptibility to Human Immunodeficiency Virus-1 Infection of Human Foreskin and Cervical Tissue Grown in Explant Culture

Susceptibility to Human Immunodeficiency Virus-1 Infection of Human Foreskin and Cervical Tissue Grown in Explant Culture. Bruce K Patterson, Alan Landay, Joan N Siegel , Zareefa Flener , Dennis Pessis , Antonio Chaviano, Robert C Bailey Am J Pathol. 2002 Sep;161(3):867–873. doi: 10.1016/S0002-9440(10)64247-2 Numerous studies have indicated a protective effect of male circumcision against acquisition of human immunodeficiency virus (HIV)-1. We investigated mechanisms responsible for the possi

NRHSResearch • Evidence • Impact

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Water, sanitation and hygiene at sex work venues to support menstrual needs

Phillips-Howard PA, Osire E, Akinyi C, Zulaika G, Otieno FO and Mehta SD (2024) Water, sanitation and hygiene at sex work venues to support menstrual needs. Front. Public Health 12:1305601. https://doi.org/10.3389/fpubh.2024.1305601 Introduction: Adequate menstrual health and hygiene (MHH) is necessary for women's health and equity of all menstruators. Female sex workers (FSW) require good MHH to prevent discomfort and exposure to pathogens. No studies have evaluated water, sanitation, and hygi

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Increased reproductive tract infections among secondary school girls during the COVID-19 pandemic: associations with pandemic-related stress, mental health, and domestic safety

Increased reproductive tract infections among secondary school girls during the COVID-19 pandemic: associations with pandemic-related stress, mental health, and domestic safety. Supriya D Mehta, Debarghya Nandi, Fredrick Otieno, Garazi Zulaika, Elizabeth Nyothach, Walter Agingu, Runa Bhaumik, Linda Mason, Anna Maria van Eijk, Penelope A Phillips-Howard Sexual Medicine (2024), Volume 12, Issue 3, June 2024, qfae045, https://doi.org/10.1093/sexmed/qfae045 Background: Kenya, like many countries,

NRHSResearch • Evidence • Impact

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Participatory development and initial pilot run of the Shauriana program to integrate sexual health and mental health support for young gay and bisexual men and other men who have sex with men in Kenya

Participatory development and initial pilot run of the Shauriana program to integrate sexual health and mental health support for young gay and bisexual men and other men who have sex with men in Kenya. Laura Jadwin-Cakmak, Gary W. Harper, Elijah Ochieng, K. Rivet Amico, Teddy Aloo, Felix Okutah, Edwin Gumbe, Kennedy Olango, Duncan O. Okall, Fredrick O. Otieno, Wilson Odero, Susan M. Graham Advances in Global Health (2025) 4 (1): 2442813. https://doi.org/10.1525/agh.2025.2442813 Gay and bisexu

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Temporal trends and transmission dynamics of pre-treatment HIV-1 drug resistance within and between risk groups in Kenya, 1986–2020

Temporal trends and transmission dynamics of pre-treatment HIV-1 drug resistance within and between risk groups in Kenya, 1986–2020. George M Nduva, Frederick Otieno, Joshua Kimani, Yiakon Sein, Dawit A Arimide, Lyle R Mckinnon, Francois Cholette, Morris K Lawrence, Maxwell Majiwa, Moses Masika, Gaudensia Mutua, Omu Anzala, Susan M Graham, Larry Gelmon, Matt A Price, Adrian D Smith, Robert C Bailey, Patrik Medstrand, Eduard J Sanders, Joakim Esbjörnsson, Amin S Hassan. Journal of Antimicrobial C

NRHSResearch • Evidence • Impact

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The Mbili Pamoja Study: Unraveling the Hidden Story of STIs and Immunity

For years, the conversation around sexually transmitted infections (STIs) has focused on detection and treatment. But what if we have been missing a crucial part of the story? Beyond just identifying infections, what if we could understand why some people are more vulnerable and how their immune system and microbiome interact with these infections? That’s exactly what the Mbili Pamoja Study is set to uncover. A Deeper Look at STI Risks Men who have sex with men (MSM) in Kenya experience high